A great period photo I believe taken in the 1960's showing the San Francisco waterfront in the background. The white freighter to the right would be a States Lines Mariner class ship at Pier 15. Pier 15-17 was States Lines headquarters prior to moving to Pier 80 in the South Bay. One of the Port of San Francisco pile drivers is alongside Pier 9S, today the home of the San Francisco Bar Pilots. I don't recognize the black hulled freighter at Pier 7S, but the warehouse portion of the pier burned about 1973, so the photo predates that. The tugboat at Pier 3S looks to be one of Red Stack's Miki class tugs. The white hulled small ship bow out at Pier 1N would be the Komoku, a small freighter engaged in transporting sugar from the refinery at Crockett up river to various receiving points in San Francisco and Richmond. Sadly, all of the activity shown in this photo including the Dintedlyk is gone today, replaced by upscale offices since the advent of containers. The tower on the hill above the Dintedlyk's bow would of course be Coit Tower.
Eric: Not sure about when the freeway was built. Fortunately, it was torn down after the 1989 earthquake. The waterfront is a much more beautiful place since it's demise. As to dating the photo, Red Stack had their headquarters at Pier 25 when I was in the schoolship from 1963 to 1966 and I recall visiting the tugs at that location and the office which was upstairs at the end of the pier. Pier 25 was demolished to build Pier 27/29 for PFEL, and Red Stack moved to Pier 3 at that time. The photo shows a Red Stack tug at Pier 3, and their small office is visible at the North side of the pier. I think the photo probably dates from the late 1960's.